Rosuvastatin+fenofibrate
About Rosuvastatin+fenofibrate
Rosuvastatin+fenofibrate is indicated in the treatment of hyperlipidemia (high lipid levels), mixed dyslipidemia (low good cholesterol and high bad cholesterol and triglycerides), hypercholesterolemia (high cholesterol) and hypertriglyceridemia (high levels of triglycerides).
Rosuvastatin+fenofibrate contains Rosuvastatin and Fenofibrate. Rosuvastatin reduces cholesterol production in the liver. Fenofibrate works by lowering the level of triglycerides in the blood and bad cholesterol. Together, Rosuvastatin+fenofibrate helps treat high cholesterol levels.
In some cases, you may experience nausea, headache, abdominal pain, muscle pain, weakness, and constipation. Most of these side effects of Rosuvastatin+fenofibrate do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Do not take Rosuvastatin+fenofibrate if you are allergic to any of its components. Consult your doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health conditions and medications to prevent any potential interactions.
Uses of Rosuvastatin+fenofibrate
Medicinal Benefits
- Rosuvastatin+fenofibrate is a combination medicine primarily used to manage abnormal lipid/cholesterol levels in the blood.
- It helps lower high levels of triglycerides (a type of fat) in the blood, which reduces the risk of pancreatitis and cardiovascular disease.
- Effectively reduces elevated cholesterol levels, especially low-density lipoprotein (LDL or 'bad cholesterol').
- Balances abnormal lipid profiles by lowering triglycerides and LDL, while increasing high-density lipoprotein (HDL or 'good cholesterol').
- It increases the uptake and breakdown of LDL cholesterol in the liver and suppresses the production of very low-density lipoprotein (VLDL), thereby reducing overall bad cholesterol levels in the blood.
- Rosuvastatin+fenofibrate enhances the activity of lipoprotein lipase, an enzyme that breaks down fats in the bloodstream. It also helps reduce uric acid levels by promoting its excretion through urine.
- It reduces the chances of complications such as heart attack, stroke, and angina (chest pain due to reduced blood flow to the heart) due to high cholesterol levels.
Directions for Use
- Rosuvastatin+fenofibrate can be taken with or without food as advised by your doctor.
- Follow your doctor's instructions on the dosage and timing of this medication.
- Swallow Rosuvastatin+fenofibrate as a whole with a glass of water.
- Do not crush, break, or chew it.
Storage
Side Effects of Rosuvastatin+fenofibrate
- Nausea
- Headache
- Abdominal pain
- Muscle pain (myalgia)
- General weakness
- Constipation
Drug Warnings
- Do not take Rosuvastatin+fenofibrate if you are allergic to any of its components.
- Inform your doctor if you have liver or kidney problems, pre-existing gall bladder disease, diabetes, muscle pain, or blood coagulation problems.
- Rosuvastatin+fenofibrate may increase the risk of muscle problems. Talk to your doctor if you experience muscle pain, tenderness or weakness, particularly if accompanied by malaise or fever.
- Consult your doctor before starting Rosuvastatin+fenofibrate if you are pregnant or breastfeeding.
- Let your doctor know if you are taking any other medicines, including supplements or herbal products.
Drug Interactions
Drug-Drug Interaction: Rosuvastatin+fenofibrate may interact with immune system affecting medicine (cyclosporine), bile affecting pills (niacin, gemfibrozil, bile acid resin), anti-HIV drugs (lopinavir, ritonavir, atazanavir, ritonavir, tipranavir/ritonavir, fosamprenavir/ritonavir), anti-coagulant or blood thinners (coumadin, warfarin), and anti-arthritis pills (colchicine). So if you are taking these drugs, tell your doctor before taking Rosuvastatin+fenofibrate.
Drug-Food Interaction: High-fat/lipid-containing food or drinks like processed foods, packaged foods, pastries, cookies, cakes, alcoholic beverages (beer) should be avoided while taking Rosuvastatin+fenofibrate.
Drug-Disease Interaction: Rosuvastatin+fenofibrate should not be given in the condition of liver diseases like biliary cirrhosis (fatty liver disease), gallstones (cholelithiasis), kidney disease, muscle disease like myopathy, and rhabdomyolysis.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended not to consume alcohol along with Rosuvastatin+fenofibrate to avoid unpleasant side effects like drowsiness, dizziness, or sleepiness. It may also lead to a life-threatening condition like coma if taken with excessive alcohol.
Pregnancy
unsafeRosuvastatin+fenofibrate contains Rosuvastatin, a pregnancy category X medicine which can harm both the pregnant mother and the unborn baby (fetus). So, please consult your doctor if you are pregnant.
Breast Feeding
cautionRosuvastatin+fenofibrate is known to pass into the breast milk and can affect the baby's health. So, please consult your doctor if you are breastfeeding.
Driving
safe if prescribedRosuvastatin+fenofibrate does not usually affect your ability to drive.
Liver
cautionRosuvastatin+fenofibrate to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.
Kidney
cautionRosuvastatin+fenofibrate to be taken with caution, especially if you have a history of kidney disease or are currently on dialysis. The dose may have to be adjusted by your doctor.
Children
cautionThe safety and efficiency of Rosuvastatin+fenofibrate has not been established in children.
Habit Forming
Diet & Lifestyle Advise
- A low-fat diet is advised to lower levels of fat in the blood.
- As a precautionary measure, you are recommended not to consume alcohol or junk food items from outside, stick to freshly prepared home-cooked meals and take proper rest for a speedy recovery.
- Replacing most of your saturated fats with unsaturated fats can reduce total cholesterol and LDL cholesterol in a short period.
- Foods like avocados, olive oil, fatty fish and nuts contain lots of heart-healthy unsaturated fats, so it’s beneficial to eat them regularly.
- Regular exercise can make your heart strong and decrease your risk of a heart attack.
Special Advise
- You should have your lipid profile test, including total cholesterol (TC), triglycerides (TG), LDL, HDL, VLDL and HDL done every 6 months to ensure whether Rosuvastatin+fenofibrate is working or not.
- Your doctor may suggest certain tests to observe the enzyme levels during medication.
- This medicine is only one part of a treatment program which should also include a healthy, low-fat diet, regular exercise, smoking cessation, moderation of alcohol intake, and weight reduction.
Patients Concern
Disease/Condition Glossary
High cholesterol: Hyperlipidemia occurs when there are too many lipids (or fats), like cholesterol and triglycerides (TG). Hypercholesterolemia is a type of Hyperlipidemia in which there is excessive low-density lipoprotein - LDL (bad cholesterol) and a low level of high-density lipoprotein - HDL (good cholesterol) in your blood. This condition increases the deposition of fats on the lining of the heart arteries, which increases the risk of heart blockage and other blood clot problems.
FAQs
Rosuvastatin+fenofibrate is used to lower increased levels of total cholesterol and triglyceride levels. This prevents the risk of having any cardiovascular events like heart attack, stroke, and heart-related chest pain (angina) in the future.
Usually, it is not safe to take Rosuvastatin+fenofibrate with fusidic acid as it may lead to muscle weakness, tenderness or pain. Please consult your doctor before taking Rosuvastatin+fenofibrate along with fusidic acid.
Rosuvastatin+fenofibrate contains Rosuvastatin and Fenofibrate. Rosuvastatin reduces cholesterol production in the liver. Fenofibrate works by lowering the level of triglycerides in the blood and bad cholesterol. Together, Rosuvastatin+fenofibrate helps treat high cholesterol levels.
Yes, taking Rosuvastatin+fenofibrate can cause muscle pain (myalgia) and long-term complications like rhabdomyolysis and myopathy. Also, please tell your doctor if you have a constant muscle weakness.
Yes, Rosuvastatin+fenofibrate can be taken at night or any other time with or without food. It is better to take it at a fixed time.
Yes, Rosuvastatin+fenofibrate can make you feel tired as it reduces the energy supply to the muscles in the body. People suffering from heart or liver diseases feel more tired while taking Rosuvastatin+fenofibrate. Please consult your doctor if you feel tired while taking Rosuvastatin+fenofibrate.
No, Rosuvastatin+fenofibrate does not cause weight gain. If you experience weight gain while you are taking Rosuvastatin+fenofibrate, please consult your doctor.
No, Rosuvastatin+fenofibrate should not be stopped even if you feel better, as it leads to worsening of your condition. Please consult your doctor if you feel better and do as advised.
Yes. Rosuvastatin+fenofibrate is also prescribed for the treatment of diabetic dyslipidemia (high cholesterol and lipid in diabetes). However, you should consult a doctor before using Rosuvastatin+fenofibrate.
Rosuvastatin+fenofibrate contains Rosuvastatin (statin) and Fenofibrate (fibric acid derivative), which help treat high cholesterol.
No, Rosuvastatin+fenofibrate is not a blood thinner. It is a cholesterol-lowering medicine.
Rosuvastatin+fenofibrate should be swallowed as a whole with water; do not crush or chew it.
Side effects of Rosuvastatin+fenofibrate are nausea, headache, abdominal pain, muscle pain, weakness, and daytime drowsiness. If the side effects are persistent, reach out to your doctor.
Liver damage is a very rare side effect of Rosuvastatin+fenofibrate. Let the doctor know if you have liver problems.
Follow a low-fat diet, avoid fried foods, exercise regularly, and do not drink alcohol.
Consult the doctor before taking Rosuvastatin+fenofibrate with other medicines like immunosuppressants, bile affecting pills, anti-HIV drugs, blood thinners and anti-arthritis pills.
Take Rosuvastatin+fenofibrate at a fixed time daily as it will help you to remember taking the medicine.
Rosuvastatin+fenofibrate should not be taken by people who are allergic to any of its components and pregnant women.
You are recommended not to consume alcohol along with Rosuvastatin+fenofibrate to avoid unpleasant side-effects like drowsiness, dizziness, or sleepiness.
Store Rosuvastatin+fenofibrate at room temperature, in a dry place. Keep out of sight and reach of children.