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Sugammadex

About Sugammadex

Sugammadex belongs to a group of medicines called Selective Relaxant Binding Agents. It is used to speed up recovery from muscle relaxants after surgery. It helps reverse the effects of these relaxants so you can breathe normally again.

Sugammadex contains sugammadex, which works by binding to muscle relaxants, neutralizing their effect. This helps your muscles start working normally again, and you can breathe properly again.

Sugammadex may cause certain side effects in some individuals, such as flushing (warmth, redness, or tingly feeling), itching, slow heartbeats, nausea, vomiting, pain, headache, light-headed feeling, cough, decreased blood pressure, injection site reactions, and shortness of breath. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Sugammadex should be avoided if you are allergic to any of its components. Before starting the treatment, inform your doctor if you have liver/kidney problems. Also, let the doctor know about your health conditions and the medications you are taking to avoid potential interactions. Consult the doctor if you are pregnant or breastfeeding before starting treatment with Sugammadex.

Uses of Sugammadex

Sugammadex is used for speeding up recovery from muscle relaxants after surgery. The detailed use of Sugammadex is as follows:
• Facilitating Post-Surgical Recovery: Sugammadex reverses the effects of certain neuromuscular blocking agents (rocuronium or vecuronium) used during surgery and helps restore normal muscle function and breathing after surgery, allowing patients to regain muscle control and breathe independently.

Medicinal Benefits

Sugammadex is Selective Relaxant Binding Agent, which is used to speed up recovery from muscle relaxants after surgery. It helps reverse the effects of these relaxants so you can breathe normally like before. It works by binding to muscle relaxants, neutralizing their effect. This helps your muscles start working normally again, and you can breathe properly.

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use. • Sugammadex should be administered by a nurse or doctor to ensure proper dosage, technique, and monitoring for any potential side effects or complications. • Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Sugammadex

  • Flushing
  • Itching
  • Slow heartbeats
  • Nausea
  • Vomiting
  • Pain
  • Headache
  • Light-headed feeling
  • Cough
  • Decreased blood pressure
  • Injection site reactions
  • Shortness of breath

Drug Warnings

Sugammadex should be avoided if you are allergic to any of its components. Before starting the treatment, inform your doctor if you have liver/kidney problems. Before taking Sugammadex, talk to your doctor if you have fluid retention (oedema) or have any bleeding disorders (disturbances in blood clotting). Consult your doctor if you are pregnant or breastfeeding before starting treatment with Sugammadex. Keep the doctor informed about your health condition, including the current medications and medical history.

Drug Interactions

Drug-Drug Interaction: Inform the doctor if you are taking anticancer drugs (toremifene), antibiotics (fusidic acid), and hormonal contraceptives (drospirenone, etonogestrel, levonorgestrel, medroxyprogesterone, norethindrone).

Drug-Food Interaction: No interactions were found.

Drug-Disease Interaction: If you have a history of kidney, liver, or bleeding problems, inform your doctor before taking Sugammadex.

Drug-Drug Interactions Checker List:

  • TOREMIFENE
  • FUSIDIC ACID
  • DROSPIRENONE
  • ETONOGESTREL
  • LEVONORGESTREL
  • MEDROXYPROGESTERONE
  • NORETHINDRONE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      It is unknown whether alcohol interacts with Sugammadex. However, it is best to avoid or limit alcohol consumption to avoid any negative complications.

    • Safety Warning

      Pregnancy

      caution

      Sugammadex is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      consult your doctor

      It is unknown whether Sugammadex passes into breast milk, so consult your doctor before using it while breastfeeding.

    • Safety Warning

      Driving

      consult your doctor

      Your doctor will advise when it is safe to drive or operate machinery after using Sugammadex.

    • Safety Warning

      Liver

      caution

      If you have an existing or a history of liver disease, inform your doctor before receiving Sugammadex.

    • Safety Warning

      Kidney

      caution

      If you have a history of kidney disease, inform your doctor before receiving Sugammadex. Dose adjustment may be needed to avoid potential effects.

    • Safety Warning

      Children

      consult your doctor

      Sugammadex is not recommended in children aged less than two years. Your doctor may prescribe this medicine if required based on your child's age, body weight, and condition.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Eat a balanced diet and stay hydrated.
    • Include antioxidant-rich foods like fruits and vegetables.
    • Limit salt and processed foods to manage blood pressure.
    • Engage in light physical activity to improve muscle strength.
    • Monitor breathing patterns.
    • Avoid alcohol and quit smoking.

    Special Advise

    • Inform your doctor that you are receiving Sugammadex before undergoing any medical check-ups, as it may affect your results.
    • Sugammadex may reduce the effectiveness of hormonal contraceptives by lowering progesterone levels. If you are using the pill, follow instructions for a missed dose. For other hormonal contraceptives, use an additional non-hormonal method (like condoms) for the next 7 days.

    Patients Concern

    Disease/Condition Glossary

    Postoperative Neuromuscular Blockade: It is a condition where muscle relaxants used during surgery last too long, causing breathing difficulties and muscle weakness. It is often caused by high doses or prolonged use of certain muscle relaxants like rocuronium or vecuronium, and can lead to complications like delayed recovery, respiratory failure, or aspiration if not properly managed.

    FAQs

    Sugammadex is used to speed up recovery from muscle relaxants after surgery. It helps reverse the effects of these relaxants so you can breathe normally again.

    Available Medicines for

    Sugammadex

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