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About TRIFAROTENE

TRIFAROTENE is used to treat acne vulgaris of the face and/or trunk when many comedones (blackheads and whiteheads), papules (small bumps) and pustules (inflammatory pimples) are present. Acne vulgaris is a common skin condition that occurs when hair follicles are blocked with dead skin cells and oil. Acne occurs due to overactive sebaceous (oil) glands in the skin. 

TRIFAROTENE contains Trifarotene, which works by unplugging blocked hair follicles and preventing the formation of such plugs in the first place.

TRIFAROTENE is for external use only. Use TRIFAROTENE as prescribed. Your doctor will advise you on how often you need to use TRIFAROTENE based on your medical condition. TRIFAROTENE may cause common side effects such as skin irritation, itching or sunburn. Most of these side effects of TRIFAROTENE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Trifarotene or any other ingredients in TRIFAROTENE, tell your doctor. You are recommended to apply a moisturizer from the beginning of treatment, which may help prevent reactions such as peeling, redness, dryness, and stinging/burning. Do not apply TRIFAROTENE on cuts, scrapes, abraded, eczematous or sunburned skin. Apply TRIFAROTENE carefully to sensitive areas of the skin such as armpits or neck. Avoid excessive exposure to sunlight, including phototherapy or sunlamps during treatment with TRIFAROTENE. Do not apply TRIFAROTENE in larger amounts than prescribed, as it does not give quick or better results but makes your skin scaly, irritated or red. 

Uses of TRIFAROTENE

Acne vulgaris (acne)

Medicinal Benefits

TRIFAROTENE belongs to a class of drugs called retinoids (synthetic vitamin A). TRIFAROTENE helps skin replace its old skin cells at a faster speed, exfoliating away the old cells in the process and helping prevent the formation of new acne. Thus, it loosens blackheads and whiteheads, making them easier to come out, stops the formation of new whiteheads and blackheads, and lowers the number of inflamed, red acne spots.

Directions for Use

Use TRIFAROTENE as advised by your doctor. Apply a thin layer of cream to the affected areas of the face (nose, chin, forehead, and right and left cheeks) and all affected trunk areas on clean and dry skin. Avoid contact of TRIFAROTENE with eyes, eyelids, lips and mucous membranes. If TRIFAROTENE comes in contact with these areas accidentally, rinse with plenty of lukewarm water immediately.

Storage

Store in a cool and dry place away from sunlight

Side Effects of TRIFAROTENE

  • Skin irritation
  • Itching
  • Sunburn

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to Trifarotene or any other ingredients in TRIFAROTENE, tell your doctor. You are recommended to apply a moisturizer from the beginning of treatment, which may help prevent reactions such as peeling, redness, dryness, and stinging/burning. If symptoms do occur, the doctor may instruct you to start using a moisturizer (if you have not already), to use the cream less often or to stop for a short time. Despite these measures, if the symptoms persist, you may be asked to stop the cream altogether. Do not apply TRIFAROTENE on cuts, scrapes, abraded, eczematous or sunburned skin. Apply TRIFAROTENE carefully to sensitive areas of the skin such as armpits or neck. Avoid waxing as a depilatory method on the skin treated with TRIFAROTENE as it may increase skin sensitivity. Avoid excessive exposure to sunlight, including phototherapy or sunlamps during treatment with TRIFAROTENE. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn. Do not apply TRIFAROTENE in larger amounts than prescribed, as it does not give quick or better results but makes your skin scaly, irritated or red. Avoid using skin products that may dry or irritate your skin, such as medicated or abrasive soaps and cleansers, products that contain high amounts of alcohol and soaps, cleansers, and cosmetics that have strong skin drying effects.

Drug Interactions

Drug-Drug Interaction: If you use other topical acne medicines containing resorcinol, sulfur, or salicylic acid, inform your doctor, as they may cause skin irritation. 

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: No interactions found.

Drug-Drug Interactions Checker List:

  • RESORCINOL
  • SULFUR
  • SALICYCLIC ACID
  • Safety Advice

    • Safety Warning

      Alcohol

      consult your doctor

      Please consult a doctor if you have any concerns regarding alcohol consumption while using TRIFAROTENE.

    • Safety Warning

      Pregnancy

      unsafe

      TRIFAROTENE is not recommended for use during pregnancy or if you plan to become pregnant. If you discover you are pregnant during treatment with TRIFAROTENE, stop using this medicine and consult a doctor immediately.

    • Safety Warning

      Breast Feeding

      consult your doctor

      When using TRIFAROTENE, there is a risk that Trifarotene passes into your breast milk, and a risk to the newborn/infant cannot be excluded. You and your doctor must make a decision whether to discontinue breastfeeding or to avoid using TRIFAROTENE, considering the benefit of breastfeeding for the child and the benefit of therapy for the mother. However, to avoid the risk of ingestion by and/or contact exposure of an infant, nursing mothers should not apply TRIFAROTENE to the chest or breast area.

    • Safety Warning

      Driving

      safe if prescribed

      TRIFAROTENE usually does not affect your ability to drive or operate machinery.

    • Safety Warning

      Liver

      consult your doctor

      If you have any concerns regarding the use of TRIFAROTENE in patients with liver problems, please consult a doctor.

    • Safety Warning

      Kidney

      consult your doctor

      If you have any concerns regarding the use of TRIFAROTENE in patients with kidney problems, please consult a doctor.

    • Safety Warning

      Children

      unsafe

      TRIFAROTENE is not recommended for children and adolescents below 12 years of age.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Avoid sun exposure while using TRIFAROTENE as it may make skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.
    • Regular exercise can improve your mood and self-esteem, though it doesn't clear acne. Take a shower immediately after finishing exercise, as sweat may irritate acne.
    • Wash your hair regularly and avoid hair falling across the face.
    • Remove the make-up completely before going to bed.

    Patients Concern

    Disease/Condition Glossary

    Acne: It is a common skin condition that occurs when hair follicles are blocked with dead skin cells and oil, causing pimples, whiteheads and blackheads. Acne affects people of all ages but is most common among teenagers. The symptoms of acne include pus-filled pimples, uninflamed (not swollen) blackheads, and red, large and tender bumps. The treatment for acne includes certain creams, cleansers and antibiotics.

    FAQs

    How does TRIFAROTENE work?

    TRIFAROTENE works by unplugging blocked hair follicles and by preventing the formation of such plugs in the first place.

    Does TRIFAROTENE make skin sensitive to sunlight?

    TRIFAROTENE may increase the skin's sensitivity to sunlight. Therefore, avoid or limit exposure to sunlight, including phototherapy or sunlamps during treatment with TRIFAROTENE. You are advised to use sunscreen with SPF (sun protection factor) at least 30 and wear protective clothing while going out to prevent sunburn.

    Can I use moisturizer with TRIFAROTENE?

    You are advised to use moisturizer before or after applying TRIFAROTENE, allowing sufficient time to let the skin dry between the moisturizer and TRIFAROTENE application.

    Can TRIFAROTENE be used with other acne medications?

    Acne medications with irritant, peeling, or drying effects should be used with caution, as they may produce additive irritant effects with TRIFAROTENE. However, if your skin becomes irritated, contact your doctor.

    Available Medicines for

    TRIFAROTENE