Four years of mucus and liquid discharge in stool is a chronic issue that requires a proper medical evaluation rather than self-medication. These symptoms can stem from several conditions, including Irritable Bowel Syndrome (IBS), Inflammatory Bowel Disease (IBD) like Crohn?s or ulcerative colitis, or localised issues like haemorrhoids (piles) or an anal fistula. Because treatment depends entirely on the specific cause, there is no single medication that can be safely recommended without a diagnosis. Please consult a gastroenterologist or primary care physician. They will likely recommend tests, such as a colonoscopy or stool analysis, to identify the root cause and prescribe the correct, targeted therapy.

If symptoms persist despite current medications, your doctor or rheumatologist may add regular NSAIDs for pain and inflammation and consider biologic injections, such as TNF inhibitors (adalimumab and etanercept) or IL-17 inhibitors (secukinumab and ixekizumab), if NSAIDs are ineffective. Daily physiotherapy exercises, posture training, and adequate intake of calcium and vitamin D are essential for maintaining spinal mobility and slowing disease progression.