I have been suffering from chronic daily migraines. Sensival (nortriptyline) 25 mg only provided partial relief, and homeopathic treatments have not helped. What alternative prescription medications or advanced preventative pharmaceutical treatments are available for managing severe, treatment-resistant migraines?
Since your current treatment provides only partial relief, several advanced, clinically proven preventative options are available. For chronic migraines, botulinum toxin injections administered every three months can significantly reduce headache days. Another highly effective, modern class of preventive drugs is CGRP pathway inhibitors; these include injectable monoclonal antibodies (such as erenumab or fremanezumab) and oral gepants. Alternatively, we can consider switching to other oral preventatives like topiramate, valproic acid, or beta-blockers such as propranolol. Please discuss these options with a neurologist to safely tailor an effective treatment plan for your specific needs.