It is completely understandable to feel anxious, but you should not skip the prescribed antibiotic, rifaximin. Unlike most antibiotics, rifaximin is not absorbed into your bloodstream and acts only locally in your gut. It is highly targeted, rarely causes diarrhea, and is actually used to treat gut bacterial overgrowth and bloating. Additionally, the co-prescribed probiotic (Saccharomyces boulardii) actively protects your healthy gut bacteria and prevents diarrhea. Together, they will help resolve your bloating and restore your appetite safely. Please complete the course as prescribed, and continue taking your metformin for diabetes as usual.