To safely remove the thick layer of Soframycin without damaging the healing skin underneath, do not scrub the area. Instead, apply a gentle oil like baby oil, mineral oil, or plain petroleum jelly (Vaseline) over the dried cream. Let it sit for 5 to 10 minutes to soften the layer. Gently wipe it away using a soft, clean cloth or sterile gauze dipped in lukewarm water. If some residue remains, do not force it off; it will shed naturally as your skin heals. Keep the area clean and seek medical advice if you notice signs of infection like increased redness or pus.