It is entirely safe to take your stomach medications, such as Pan-D (pantoprazole with domperidone) or Sompraz 40 (esomeprazole), for your acid reflux. There are no known interactions between these medications and the Covishield vaccine you received 10 days ago, and they will not interfere with how well the vaccine works to protect you. You can safely manage your stomach irritation with them. Try to eat smaller, non-spicy meals and stay well-hydrated to help soothe your stomach. If your symptoms do not improve in a few days, please consult your healthcare provider.