For erectile dysfunction with diabetes and high blood pressure, oral medications called PDE5 inhibitors such as sildenafil (Viagra) or tadalafil (Cialis) are commonly prescribed and highly effective. However, it is vital to consult your doctor before taking them. These medications can interact dangerously with certain blood pressure drugs, particularly nitrates, causing a life-threatening drop in blood pressure. Furthermore, keeping your blood sugar and blood pressure well-controlled is essential, as poorly managed levels damage the blood vessels, causing the issue. Your doctor will review your current medications and health status to safely prescribe the right treatment for you. Avoid self-medicating or using unregulated supplements.