Why might a child with enteric fever experience a temperature spike to 103?F 24 hours after starting Taxim O Forte, when their baseline fever was previously 101?F?
It is quite common for a child's temperature to fluctuate or spike briefly during the first 24 to 48 hours of starting an antibiotic like Taxim O Forte (cefixime) for enteric fever. This happens because the medicine is actively fighting the bacteria, which can temporarily release substances that trigger a fever spike as they are destroyed. It usually takes 48 to 72 hours for the antibiotic to fully stabilize the fever. Please continue the medication as prescribed, keep your son hydrated, and consult your pediatrician for fever-reducing measures if he remains uncomfortable.
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Why might a child with enteric fever experience a temperature spike to 103?F 24 hours after starting Taxim O Forte, when their baseline fever was previously 101?F?