Yes, switching to generic cardiac medications is generally safe, as approved generics contain the same active ingredients, strength, and efficacy as branded drugs. Since the active components are identical, you do not need to taper the doses; the transition can be made directly. However, because managing post-bypass cardiac health is critical, please consult his cardiologist before making any changes. His doctor can confirm the quality of the specific generic substitute and help prevent any confusion, as generic pills may differ in shape, size, or colour from his current medication. Never alter his regimen without professional medical guidance.