Trikonol 10 (amitriptyline, the active ingredient in your medicine) is generally safe for long-term use under medical supervision, especially at a low dose of 10 mg. While most people tolerate it well, long-term use can sometimes cause mild, manageable side effects like dry mouth, constipation, slight drowsiness, weight gain, or minor changes in vision. It is important not to stop this medication suddenly, as doing so can cause withdrawal symptoms. I recommend regular follow-up visits with your doctor to monitor your progress and ensure your overall health remains excellent. Please consult your physician before making any changes to your therapy.