It is generally safe to take griseofulvin in the morning and Tryptomer (amitriptyline) at bedtime as you have planned. Spacing them out this way is a wonderful approach to help minimize daytime drowsiness. Griseofulvin can sometimes cause your body to process amitriptyline more quickly, which might slightly lower its effectiveness, but taking them at separate times is very manageable. Please let your doctor know about this schedule so they can monitor your progress and ensure you get the best results from both treatments.
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Is it safe to take griseofulvin and Tryptomer on the same day, such as taking griseofulvin in the morning and Tryptomer at bedtime?