Upadoz is generally well-tolerated. Some people may experience mild side effects such as dizziness, headache, nausea, or tiredness. Serious complications are uncommon, so regular medical check‑ups are important. The safe duration of use depends on various factors, including your medical condition, response to treatment, age, other medications you may be taking, and your doctor’s assessment of benefits versus risks. Always take it exactly as prescribed and inform your doctor if you notice any unusual symptoms.