Gallstones are small, hard deposits that form in the gallbladder, usually from cholesterol. In your case, the stones are 13 mm and 8.5 mm, which are moderate to large in size. Medicines are generally not very effective for stones of this size. Drugs such as ursodeoxycholic acid may help dissolve certain cholesterol stones, but they work very slowly, often taking many months or even years. They are mainly useful when the stones are small and soft and when the gallbladder is functioning normally. Even if the stones dissolve, they can recur after stopping the medication. If the stones are not causing symptoms, doctors may suggest regular monitoring and lifestyle changes, such as eating a low-fat diet and maintaining a healthy weight. However, if you experience repeated pain, especially after fatty meals, or develop complications like fever, the most effective and permanent treatment is surgery to remove the gallbladder. This is usually done through a simple laparoscopic procedure and is considered safe. It is important to consult a doctor before trying any treatment, as self-medication may delay proper care.