Why do my spouse's severe stomach pain and bloating get twice as bad whenever she takes her prescribed medications (Colonaspa, Veloz L, and Rixmin) for suspected irritable bowel syndrome (IBS)?
While Colonaspa (mebeverine), Veloz L (rabeprazole and levosulpiride), and Rixmin (rifaximin) are prescribed to treat IBS, they can sometimes cause temporary worsening. For instance, rifaximin targets gut bacteria, which can temporarily release gas and increase bloating as the bacteria die off. Additionally, medicines affecting gut motility can initially cause cramping. Please reassure her that this can happen, but it is highly important to contact her doctor. They can easily evaluate these symptoms, ensure she is tolerating the medications well, and adjust her treatment plan to help her find the relief she deserves.