Yes, it is generally safe for you to enjoy your road trip! To prevent motion sickness, you can take generic dimenhydrinate or meclizine about an hour before travel. Your Vicks menthol lozenges are wonderful for comforting, temporary relief. For high-altitude symptoms, staying well-hydrated and ascending gradually will help. You may also consult your doctor about carrying generic acetazolamide for altitude sickness prevention. During the drive, try to sit in the front seat, keep the window cracked for fresh air, and take frequent breaks.