Back and neck pain, along with a feeling that one hand is colder than the other, especially with increased workload, is often related to muscle strain or a nerve problem in the neck, such as Cervical Spondylosis, where pressure on nerves or blood vessels can cause pain, stiffness, and altered sensations like coldness, tingling, or weakness in one arm. Poor posture, long hours of sitting, or repetitive work commonly contribute to this. In some cases, reduced blood flow or vascular issues may also play a role, especially if the temperature difference is noticeable. While mild cases improve with rest, posture correction, neck exercises, and physiotherapy, persistent or worsening symptoms should be evaluated by a doctor to rule out nerve compression or circulation problems and to start appropriate treatment.