Continuing levocetirizine (Xyzal) is excellent for controlling your hives; tracking and avoiding food triggers will also help. For the dark spots, gentle topical treatments like azelaic acid are safe for your skin and won't impact your kidney stones or uric acid levels. Since weight and high uric acid are connected, a balanced, low-purine diet can help manage both safely. Please consult a dermatologist and your primary care doctor to tailor this plan safely to your needs.

Since your symptoms have progressed despite using oral steroids (Zampred), antihistamines (Xyzal M, Alaspan), antibiotics (Agithral, Clindatime), and topical creams (Fucibet, Chitomesh SF), this may indeed be an adverse reaction, drug allergy, or contact dermatitis. Your most important next step is to stop applying the topical creams and consult a dermatologist or urologist immediately. They can safely assess the area, perhaps perform a skin biopsy or patch test, and find a gentle, targeted way to help you heal comfortably.

Xyzal M syrup (which contains levocetirizine and montelukast) is helpful for allergies, but using it continuously for a year is not recommended without close pediatric supervision. A persistent cough in a three-year-old deserves a thorough evaluation by his doctor to find the root cause, such as asthma or environmental triggers, rather than relying on long-term daily medication. Please consult his pediatrician to safely review his symptoms and discuss a tailored treatment plan.

Your current routine may be failing because Dosetil cream (desoximetasone), a strong topical steroid, can cause rebound flare-ups or worsen underlying fungal or bacterial issues when used long-term. The white spots and bumps suggest a complex skin condition that steroids alone cannot resolve. Additionally, stopping your antihistamine, levocetirizine (Xyzal), can allow itching and inflammation to flare up. Because recurring rashes require identifying specific triggers, please consult a dermatologist.

I understand how concerning this must be, but please be reassured that while uncomfortable, elevated IgE and eosinophils are typical signs of an active allergic response rather than a dangerous condition. Your hives and blood markers suggest your immune system is still reacting, possibly triggered by the recent infection or even the antibiotic itself. To help bring these levels back to normal, we need to address the underlying trigger. I highly recommend consulting an allergist. In the meantime, resuming levocetirizine (Xyzal) or using cool compresses can help soothe the itching.

Since your symptoms are spreading, worsening with sun exposure, and not improving with Caladryl lotion or levocetirizine (Xyzal), it is important to see a healthcare professional or dermatologist promptly. You may be experiencing a photosensitivity reaction or another condition that requires targeted prescription treatment. In the meantime, please stay out of direct sunlight, wear sun-protective clothing, and avoid hot showers which can worsen the burning. Applying a cool, damp compress may help soothe your skin. Please seek a professional medical evaluation soon so you can get the right care and find relief.