Please take your wife to the hospital immediately. An oxygen level dropping to 87%, especially during pregnancy, requires urgent medical evaluation to ensure both she and the baby are getting enough oxygen. While her daytime levels are 94-95% on the oxygen concentrator, these morning drops and severe shortness of breath mean her current home therapy is not sufficient. Hospitalization will allow doctors to safely monitor her asthma and COVID-19, adjust her medications like Medrol (methylprednisolone) and Budesal, and provide close monitoring for the baby. Please do not delay; seeking hospital care right away is the safest step for their well-being.

As the antihistamine provides relief, your symptoms could be due to contact dermatitis (an allergic reaction to something touching your skin) or chronic hives. For long-term management, identifying and avoiding personal triggers is key. A doctor may recommend a daily, non-drowsy antihistamine or mild topical corticosteroid creams for flare-ups. I highly recommend visiting a dermatologist or allergist for a personalized evaluation to find lasting relief.

Between the two, fexofenadine (Allegra) is generally safer than cetirizine (CZ3) because it is less likely to cause severe drowsiness. However, the 120 mg dose of Allegra is too high for someone with kidney disease. For patients on dialysis, a reduced dose of fexofenadine?typically 60 mg once daily?is much safer to prevent the medicine from building up in your body. Please speak with your nephrologist before taking either medication so they can safely prescribe the correct dose and ensure it does not interact with your other treatments.

It is very common for ongoing allergies themselves to cause inflammation and swelling inside your nose. Regarding your medications, Allegra (fexofenadine) helps reduce this swelling and is highly unlikely to cause it. However, certain nasal sprays, especially if used for too long or if they cause local irritation, can sometimes lead to dryness or a rebound swelling effect. Please be reassured that this is a manageable issue. I recommend discussing the specific nasal spray you are using with your doctor to see if adjusting your treatment can help bring you some comfort.

Since this has lasted ten days, it could be triggered by a delayed allergic reaction to a new product (like soap or lotion), a viral infection, or even stress. Because antihistamines like fexofenadine aren't helping, it is best to have a doctor or dermatologist examine your skin. They can provide a precise diagnosis and prescribe targeted treatments, like topical creams, to help you find relief quickly.

Since antihistamines and antifungals haven't helped, a key consideration is scabies, a very common and highly treatable skin condition caused by tiny mites. Other possibilities include contact dermatitis or a viral rash. I highly recommend visiting a healthcare provider for a physical exam. If it is scabies, they can prescribe highly effective targeted treatments, such as topical permethrin cream or oral ivermectin. Washing your clothes and bedding in hot water will also help clear it.