Atogla Probio is a probiotic supplement containing beneficial bacteria, and it is generally considered safe when taken as prescribed by your doctor. It may be given to support gut health and is sometimes used as an add-on in conditions such as eczema, dry skin, or atopic dermatitis. Your IgE level of 397 is elevated in many laboratories and can be associated with allergies, eczema, asthma, or other conditions, but IgE alone does not identify the exact cause. Atogla Probio does not directly lower IgE; your doctor may have prescribed it as supportive treatment based on your symptoms. Continue it for the prescribed 3 months unless your doctor advises otherwise, and consult them if you develop significant side effects or have questions about the reason for the treatment.