Since the redness, swelling, and pain are worsening despite using povidone-iodine (Betadine), it is very important to have a doctor evaluate it. This could be a deeper bacterial infection that requires oral antibiotics or professional drainage, which topical treatments cannot cure. In the meantime, you can soothe the area by soaking your thumb in warm water for 15 minutes, three to four times a day, and gently patting it dry. Please do not try to squeeze or pop the swelling yourself, as this can spread the infection. Please see a healthcare provider soon so they can help you feel better.
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What should I do if my thumbnail infection is getting worse with constant pain and red swelling, even though I have been using Betadine?