While Betadine is a good antiseptic, it may not target the specific root cause of your sores, which could be viral, bacterial, or simply a skin irritation. Sometimes, antiseptic use on sensitive skin can even delay healing. I gently recommend stopping the Betadine and seeing a healthcare provider or visiting a clinic. They can easily swab the area to find the exact cause and prescribe the correct, targeted treatment to help you heal quickly and comfortably.

Since you gargled and spit it out a day ago and feel completely fine, there is no need to worry. Betadine First Aid contains a higher concentration of povidone-iodine (usually 10%) compared to the Betadine Oral gargle (typically 1%), and may have inactive ingredients not meant for oral use. However, because you did not swallow it and have experienced no throat irritation, nausea, or stomach upset after 24 hours, your body has not absorbed any harmful amounts. Just drink plenty of water to flush out any remaining residue and use only oral-specific products in the future.

A painful, swollen penile ulcer with discharge can happen for several common reasons. It might be due to a sexually transmitted infection, such as herpes simplex virus or syphilis, or a bacterial infection that started from minor irritation. Since topical povidone-iodine (Betadine) hasn't cleared it, it is very important to see a healthcare provider soon. They can perform a physical exam, take a gentle swab of the ulcer, and run blood tests to find the exact cause. This will help them prescribe the right targeted treatment, like antibiotics or antivirals, to help you heal quickly.

Your current routine is safe and very reasonable. Avoiding sodium lauryl sulfate (SLS) is excellent, as it prevents further irritation to your lip. Vitamin B12 (Methycobal) supports tissue healing, and a povidone-iodine (Betadine) rinse helps keep the area clean, though it should be used sparingly to avoid dryness. For the painful sores, a simple over-the-counter protective paste or a mild anesthetic gel containing lidocaine can offer targeted relief. Please stay hydrated and avoid spicy or acidic foods that might sting. If the sores do not improve within ten days or worsen, please consult a doctor for a physical evaluation.

It is safe to use both Betadine (povidone-iodine) gargle and Orasep gel (anesthetic/antiseptic gel) together, as they serve different purposes. To use them effectively, rinse with the povidone-iodine gargle first to clean the area and prevent infection. Spit it out, wait about 10 to 15 minutes, and then apply a small dab of Orasep gel directly to the cut to help relieve pain. Avoid eating or drinking for 30 minutes after applying the gel. If the cut is deep or doesn't improve within a few days, please have a healthcare professional check it.

Since you previously had an infection and a boil treated with Betadine, this ongoing tenderness could be due to deep scar tissue, a minor cyst, or low-grade, persistent irritation. I recommend having a healthcare provider or dermatologist examine it to ensure there is no hidden infection. In the meantime, try to avoid tight clothing that rubs against the area, and clean it gently with a simple saline solution rather than harsh chemicals.