Yes, taking Deviry (medroxyprogesterone acetate) can indeed cause constipation. Progesterone-like hormones can relax the muscles in your digestive tract, which sometimes slows down your digestion. Please be reassured that this is a very common and usually temporary side effect. To help ease this, try drinking plenty of water and adding more fiber-rich foods to your diet. If the constipation becomes troublesome or persists, please let your doctor know so they can help you find relief.

After finishing a course of Deviry (medroxyprogesterone acetate), it typically takes about 3 to 10 days?and sometimes up to 14 days?for your period to start. Since you have PCOD, your hormone levels can take a little longer to respond and adjust, even while taking metformin. I recommend waiting a few more days. If your period still hasn?t started by day 14, or if you suspect pregnancy, please reach out to your gynecologist for a quick check-in.

Typically, you can expect your bleeding to start within 2 to 10 days after finishing your five-day course of Deviry (medroxyprogesterone). Please do not take Meprate 10mg right now. Both Deviry and Meprate contain the exact same active medicine. Taking additional medication is unnecessary and could delay your period further or upset your hormone levels. I recommend waiting for up to 10 to 14 days after your last dose. If your period still does not start by then, please consult your doctor for a gentle evaluation.

A 'mild bulky uterus' simply means her womb is slightly larger than average, often due to temporary hormonal fluctuations. 'Grade 1 fatty liver' is a mild, reversible buildup of fat, frequently linked to hormonal imbalances like PCOS, which can also cause missed periods and a lack of bleeding after Deviry (medroxyprogesterone acetate). Lifestyle changes, including a balanced diet and regular exercise, can reverse the fatty liver and help restore her hormonal balance. I highly recommend she consult her gynecologist to safely investigate the underlying cause of her missed periods and guide her treatment.

Since you have already ruled out pregnancy and other concerns, using medroxyprogesterone acetate (Deviry) is generally a safe option to help induce a bleed. However, because the previous course of norethisterone (Sysron NCR) did not trigger a period, it is possible your body's estrogen levels are currently too low to build up the uterine lining. While medroxyprogesterone is safe, it may not be fully effective if estrogen is low. I highly recommend discussing this with your gynecologist, who can check your hormone levels and safely guide your next steps.

You should continue taking the medication for the full number of days prescribed by your doctor, rather than stopping now. The spotting you are experiencing is not your actual period. Your normal menstrual flow is expected to start a few days after you finish the entire course of the pills. However, if you experience heavy bleeding or severe pain, please consult your healthcare provider.