Deviry (medroxyprogesterone acetate) is a hormone that can indeed temporarily shift your cycle, delaying both ovulation and your next period as your body readjusts. Since your ultrasound and thyroid results are normal?which is wonderful news?this delay is likely just a temporary hormonal pause. First, take a home pregnancy test if applicable. If negative, give your body a little more time to settle. I highly recommend discussing this with your gynecologist, who can guide you on the next gentle steps to safely restore your regular cycle.

This can sometimes happen when taking Deviry (medroxyprogesterone acetate) due to temporary hormonal changes, or it might be related to the underlying cause of your irregular periods, like Polycystic Ovary Syndrome (PCOS). I highly recommend scheduling a follow-up with your gynecologist. They can evaluate your hormone levels, discuss if a different medication is better suited for you, and help manage this symptom safely. Please continue taking your medication as prescribed until you speak with them.

Since you have already ruled out pregnancy and other concerns, using medroxyprogesterone acetate (Deviry) is generally a safe option to help induce a bleed. However, because the previous course of norethisterone (Sysron NCR) did not trigger a period, it is possible your body's estrogen levels are currently too low to build up the uterine lining. While medroxyprogesterone is safe, it may not be fully effective if estrogen is low. I highly recommend discussing this with your gynecologist, who can check your hormone levels and safely guide your next steps.

Since stopping oral contraceptives, your body may need time to recalibrate, but we can actively manage these symptoms. Clinically, we often consider generic spironolactone to block excess androgens or generic metformin to help regulate cycles, especially if insulin resistance is a factor. On the lifestyle side, focusing on a balanced, low-glycemic diet and regular, enjoyable exercise can significantly support hormone balance. I highly recommend consulting an endocrinologist or gynecologist.

A missed period for 40 days with a negative pregnancy test is often due to a hormonal imbalance, which can be triggered by stress, weight changes, excessive exercise, or conditions like Polycystic Ovary Syndrome or thyroid problems. In many cases, it is not serious, but it should be evaluated if it happens repeatedly. Treatment depends on the cause. Your doctor may advise lifestyle changes (healthy diet, regular exercise, stress management), check hormone levels, and sometimes prescribe medicines like progesterone (e.g., Deviry) to help induce a period. It is also a good idea to repeat the pregnancy test if there was any recent risk, or get a blood test for confirmation. If your cycles continue to be irregular or absent, a proper medical evaluation is important to ensure the right treatment and prevent long-term issues.

After completing a course of medroxyprogesterone (Deviry), it is very common and normal for withdrawal bleeding to take anywhere from 3 to 10 days?and sometimes up to two weeks?to begin. Since it has only been five days and your pregnancy tests are negative, your body likely just needs a little more time. I recommend waiting another week. If you still haven't started bleeding 14 days after your last pill, please consult your gynecologist.