Yes, Duphaston and Jigest are essentially the same medication. They both contain the active generic hormone called dydrogesterone, which is used to support your reproductive health or pregnancy. Since they share the exact same active ingredient, they work in the same way within your body. It is very common for different companies to produce the same medicine under different brand names. You can feel completely reassured, but it is always a good practice to let your doctor know if you are switching between brands.