Nausea and weight gain can happen with some migraine and depression medicines, especially after regular use for a long time. Fluner 10 is known to sometimes increase appetite, cause weight gain, tiredness, or low mood in certain people. Nexito 10 may also cause nausea, stomach discomfort, or weight changes in some individuals, especially during long-term treatment. The combination of medicines, reduced activity, sleep changes, and depression itself can also affect body weight. Do not stop or change these medicines suddenly on your own because migraine and mood symptoms may worsen again. Light exercise, regular meal timing, proper sleep, and reducing junk food may help control weight to some extent. Sometimes doctors adjust doses or switch to alternative medicines if side effects become intolerable. Inform your psychiatrist or neurologist about the nausea and weight changes so the treatment plan can be reviewed safely. A medical review becomes more important if vomiting, severe mood changes, excessive sleepiness, or rapid unexplained weight gain continue to increase.