Fungal infections, perspiration irritation, allergies, dry skin, eczema, diabetes, and even irritation from frequent use of numerous lotions and medications can cause persistent groyne itching without a visible rash. Wear loose cotton underwear, keep the region clean and fully dry, refrain from scratching, and refrain from applying several creams?especially those that include steroids?without a doctor's consultation as they may exacerbate the condition. It is important to see a dermatologist for a thorough examination and possibly tests to determine the precise cause because antibiotics, permethrin, and other therapies have not worked. If you have redness, sores, swelling, discharge, or intense burning, get medical help as soon as possible.