A swollen thyroid and cold sensitivity most commonly point to an underactive thyroid (hypothyroidism), which is highly treatable and rarely cancer. Thyroid issues frequently overlap with PCOS. Your current medications, including Glycomet SR (metformin), Normoz, and Eva Care syrup, are prescribed to manage PCOS and do not cause thyroid swelling. I highly recommend consulting your doctor for a simple thyroid blood test and an ultrasound to get clear answers and peace of mind.

With an HbA1c of 8.5%, your blood sugar is a bit high, but we can absolutely get it to a safer range. Metformin sustained-release is a gentle, effective starting medication. However, because your HbA1c is 8.5%, starting with a combination of sitagliptin and metformin may help lower your levels more quickly and effectively. Sitagliptin helps your body release more insulin when needed, while metformin reduces sugar production in your liver. Together, they offer stronger results than metformin alone with very little risk of low blood sugar.

A creatinine of 1.85 and changes in kidney echotexture indicate early-stage kidney strain, which is common with diabetes and high blood pressure. Switching her medication from Olemzest CH 40 (olmesartan/chlorthalidone) to Cilacar (cilnidipine) is often done to protect the kidneys, as Cilacar can improve blood flow to these organs. It is safe to use alongside her diabetes medication, Glycomet (metformin). Please consult her doctor to monitor her kidney function and ensure her lifestyle support is optimal.

Sudden swelling is very rarely a sign of cancer, which typically develops slowly. Instead, it is much more commonly caused by a mild infection, a swollen lymph node, or thyroid inflammation. Your PCOS medications?Glycomet SR (metformin), Normoz, and Evacare?are not known to cause throat swelling, though a rare allergic reaction is always possible. I highly recommend having a doctor examine your throat in person to find the exact cause and give you peace of mind. Please seek immediate care if you have trouble breathing or swallowing.

While you are actively taking Yasmin (a contraceptive pill), your chances of getting pregnant are extremely low, as its main job is to prevent pregnancy. The other medications, Glycomet SR (metformin) and Normoz (myo-inositol), help manage insulin levels and support your metabolism, which actually helps prepare your body for a healthy pregnancy in the future. If you are hoping to conceive, you will just need to safely stop taking Yasmin under your doctor's guidance.

You should generally not eat below your resting metabolism (BMR), as your body needs those basic calories just to function safely. Instead, aim for a modest deficit below your total daily energy expenditure. Regarding your medication, stopping Glycomet (metformin) can certainly cause your weight loss to stall. This medication helps manage insulin resistance, which is a key factor in PCOD-related weight gain. Stopping it can make weight management much harder. Please consult your doctor before making any changes to your medication, as they can help find the safest path forward for you.