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  5. Why might a patient with suspected rheumatoid arthritis (RF: 37.2 IU/mL, anti-CCP: 0.49) continue to experience persistent pain in the soles of the feet, back of the knees, and other joints after one month of treatment with hydroxychloroquine 200 mg and methotrexate, and how long do these medications typically take to show clinical improvement?

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Why might a patient with suspected rheumatoid arthritis (RF: 37.2 IU/mL, anti-CCP: 0.49) continue to experience persistent pain in the soles of the feet, back of the knees, and other joints after one month of treatment with hydroxychloroquine 200 mg and methotrexate, and how long do these medications typically take to show clinical improvement?

Asked by Male, 36 · 1 month ago

Medications like methotrexate and hydroxychloroquine are slow-acting and typically take 6 to 12 weeks?and sometimes up to six months?to build up in your system and show significant clinical improvement. Your ongoing pain in your feet, knees, and joints is likely because these medications haven't had enough time to fully control the inflammation. Please keep your rheumatologist updated; they can help manage your current discomfort with temporary relief.
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Why might a patient with suspected rheumatoid arthritis (RF: 37.2 IU/mL, anti-CCP: 0.49) continue to experience persistent pain in the soles of the feet, back of the knees, and other joints after one month of treatment with hydroxychloroquine 200 mg and methotrexate, and how long do these medications typically take to show clinical improvement?

Answered 1 month ago

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