Ciplox Eye/Ear Drops are generally well-tolerated when used as directed. Some people may experience mild and temporary irritation, such as a slight burning or stinging sensation, especially during the first few applications. This is usually harmless and subsides quickly. However, if you notice persistent discomfort, redness, or any unusual symptoms, it’s best to consult your doctor for further guidance. Always follow the prescribed dosage and application instructions for safe and effective use.