The recommended dosage of Pi-40 D Capsule (Domperidone and Pantoprazole) is usually once daily, taken 30-60 minutes before a meal, preferably in the morning. If your doctor prescribes it twice daily, take the second dose before dinner. Swallow the capsule whole with a glass of water, and do not crush, chew, or break it. Always follow your doctor’s instructions regarding the dosage for the best results.