1. Medication Differences:

   • Riomet Duo contains glimepiride and metformin, which increase insulin secretion and improve insulin sensitivity.
   • Pioz contains pioglitazone, which enhances insulin sensitivity through a different mechanism.

2. Dosage and Frequency:

   • These medications have different dosing schedules and effects. Substitution should only occur under direct medical supervision.

3. Doctor's Prescription:

   • Confirm the online prescription with your doctor to ensure you understand the new medication regimen and how to monitor your blood sugar levels.

4. Monitoring:

   • Regularly monitor blood glucose and watch for side effects after switching medications.

If you have concerns or experience unusual symptoms, contact your healthcare provider promptly. Always follow professional advice when changing medications.