Severe joint pain accompanied by widespread oedema (swelling) may be caused by kidney problems, heart failure, autoimmune disorders (such as rheumatoid arthritis), or systemic inflammatory conditions. You should see a doctor promptly for blood tests, urine tests, and imaging to determine the underlying cause. Early diagnosis and treatment are crucial to prevent complications, manage symptoms, and protect your organs and overall health.

Swelling in one leg can be a sign of deep vein thrombosis (a blood clot in a deep vein), especially in someone with heart disease. She should seek medical attention immediately for a thorough evaluation, which may include an ultrasound and blood tests. Prompt treatment with anticoagulant medications (such as heparin or warfarin) is crucial to prevent clot progression and serious complications like pulmonary embolism.

Pulmonary oedema (fluid buildup in the lungs) cannot be diagnosed from a blood test alone. It is usually diagnosed using imaging tests, such as a chest X-ray or an echocardiogram. Pulmonary embolism (a blood clot in the lungs) may be suspected with a D-dimer blood test, but confirmation requires imaging, such as a CT pulmonary angiogram. Both conditions can be serious, so if you experience sudden shortness of breath, chest pain, or a rapid heartbeat, seek immediate medical attention.