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  5. My doctor advised me to apply Tretin inside my mouth for a white spot on the inner wall of my cheek. Is that safe?

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My doctor advised me to apply Tretin inside my mouth for a white spot on the inner wall of my cheek. Is that safe?

Asked by Male, 40 · 16 days ago

Tretin (which contains Tretinoin 0.025% w/w) is a topical retinoid meant only for external skin use and is not recommended for use inside the mouth, as it can irritate or damage the delicate oral lining. It may be used in exceptional cases after specialist evaluation, but this is not ordinary or routine use. It’s best to reconfirm with your doctor or an oral specialist to ensure the correct medicine is being used. There are specific treatments made for oral conditions, and your doctor can guide you to a safer and more suitable option.
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Here's some information about tretinoin and its use for white spots inside the mouth:

  1. What is Tretin (Tretinoin 0.025% W/W):

    • Tretinoin is a topical retinoid derived from vitamin A.
    • It is commonly used in dermatology to treat skin conditions like acne and wrinkles by promoting skin cell turnover and reducing oil production.
  2. Use of Tretinoin Inside the Mouth:

    • Using tretinoin inside the mouth is considered an off-label use, meaning it is not its primary approved indication.
    • When applied to the oral mucosa (inner cheek), it may help in managing certain lesions by encouraging cell renewal.
    • The mucosal tissue inside the mouth is very sensitive, so extra caution is needed to avoid irritation or damage.
  3. Treatment of White Spots on Inner Cheek:

    • White spots can be caused by various conditions such as leukoplakia (a potentially precancerous lesion) or lichen planus (an inflammatory condition).
    • Tretinoin might be used to help manage some of these lesions, but a proper diagnosis by a specialist is essential before starting treatment.
  4. Application Instructions and Safety:

    • If prescribed, tretinoin should be applied carefully to the affected area inside the mouth, usually in a thin layer.
    • Frequency and duration depend on the doctor’s advice.
    • Possible side effects include irritation, redness, or discomfort in the treated area. If these occur, inform your doctor promptly.
  5. When to Consult a Specialist:

    • It is important to have a dental specialist or dermatologist evaluate the white spots before using tretinoin.
    • Regular monitoring and follow-up are necessary to assess treatment response and adjust therapy if needed.
  6. Summary and Advice:

    • Tretinoin use inside the mouth should only be done under medical supervision.
    • Please consult a dermatologist or oral medicine specialist before starting tretinoin for white spots on the inner cheek to ensure safe and effective treatment.

If you experience any worsening symptoms or new concerns, seek medical advice promptly.

Answered 16 days ago

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