Please be reassured that this is a very common reaction to Isotroin (isotretinoin) known as purging. In the first few weeks, the medication works by pushing deep, trapped blockages to the surface, which temporarily makes breakouts look worse. This actually shows the medicine is doing its job. Since other therapies didn't work, isotretinoin is still your strongest ally. Please continue with a gentle skincare routine, avoid picking at your skin, and keep your dermatologist updated on your progress.

While mild facial puffiness can occasionally occur due to the skin dryness and sensitivity caused by isotretinoin (Isotroin), significant swelling is not a common side effect. Please share this with your doctor to ensure you are safe. As for green tea, enjoying a cup or two a day is perfectly safe and won't interfere with your medication. Just avoid concentrated green tea supplements, as they can put extra strain on your liver, which isotretinoin already processes. Stay hydrated.

Neither Isotroin-20 (isotretinoin) nor Azifast (azithromycin) typically causes hair growth. Instead, this is often linked to underlying hormonal fluctuations, which might also have triggered your acne. A typical course of isotretinoin lasts about 4 to 6 months, depending on your cumulative dose. Since your acne has beautifully cleared, you can safely manage the unwanted hair with temporary methods like threading or shaving, or long-term options like laser hair reduction. I highly recommend consulting your dermatologist or a gynecologist to evaluate your hormone levels and find the best long-term solution.

For severe cystic acne, a low dose of oral isotretinoin (10 mg) can take much longer to work, and sometimes a higher dose is needed to see significant improvement. Your topical clindamycin and benzoyl peroxide are excellent for surface bacteria, but deep cysts often need stronger internal treatment. Dark spots also take time to fade once the acne clears. I highly recommend discussing your progress with your dermatologist, as they can safely adjust your isotretinoin dose to help you get the clear skin you deserve.

Generally, combining oral isotretinoin (Isotroin) with topical tretinoin (found in Supatret C) is not recommended. Because both medications are strong retinoids, using them together can lead to severe skin dryness, redness, and irritation. While the topical antibiotics clindamycin and nadifloxacin (Nadoxin) are sometimes used, oral isotretinoin is incredibly effective on its own, and additional topicals are often unnecessary and can compromise your skin barrier. I highly recommend discussing this with your dermatologist to create a gentle, safe, and effective plan tailored just for you.

Because oral isotretinoin (Isotroin-30) makes your skin highly sensitive, combining it with topical clindamycin/benzoyl peroxide (Peroclin 2.5%) can cause irritation that leads to dark spots, or post-inflammatory hyperpigmentation. I recommend temporarily stopping the topical gel to let your skin rest. Focus on a gentle skincare routine with a mild cleanser and a generous amount of moisturizer. Most importantly, apply a broad-spectrum sunscreen daily, as sun exposure worsens hyperpigmentation. Please consult your dermatologist so they can safely adjust your regimen and help fade these spots.

Yes, it is safe to take Isotroin 20mg instead of Isotane 20mg. Both of these are brand names for the exact same active generic medication, isotretinoin, at the same 20mg strength. Because they contain the same active ingredient, they work the same way in your body. You can safely make this switch, but I always recommend double-checking with your pharmacist or prescribing doctor.

Consult your dermatologist if you experience skin swelling in patches with severe itching, as it could be an indication of a skin reaction.

Isotroin works best when taken with or after a meal, especially one containing a little healthy fat. Involym can be taken on an empty stomach or with food if it causes stomach upset.