The recurring swelling you are experiencing is likely angioedema. A highly common cause in patients with high blood pressure is a class of medications called ACE inhibitors (such as lisinopril), which can trigger this reaction even after years of uneventful use. Aspirin can also sometimes cause or worsen this swelling. Please consult your physician or cardiologist immediately to review your medication list. They can safely transition you to an alternative blood pressure medication (like an Angiotensin Receptor Blocker or Calcium Channel Blocker) and evaluate your aspirin use. Do not stop taking your heart medications without direct medical supervision, as doing so could be dangerous.