Yes, both Medrol (methylprednisolone) and Defza (deflazacort) are corticosteroids that can absolutely cause these symptoms. Steroids can significantly impact your mood, sleep, and concentration, leading to fatigue and feelings of sadness. Please do not stop or change your dose suddenly, as this needs to be done safely. I gently encourage you to speak with your doctor about how you are feeling. They can help adjust your treatment or find alternative options so you can feel like yourself again.
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Could my asthma medications, Medrol or Defza, be causing my constant tiredness, difficulty concentrating, and feelings of sadness?