You may use creams containing skin-lightening agents such as mild hydroquinone, kojic acid, or niacinamide. Apply only to the affected areas, use sunscreen on exposed skin, and avoid long-term unsupervised use. Please consult your doctor before using these creams to rule out any underlying conditions.

For dark facial pigmentation (likely melasma or sunspots), your wife should consult a dermatologist for a proper diagnosis. Commonly prescribed medicated creams contain active ingredients like Hydroquinone (a skin-lightening agent), Tretinoin (a retinoid to boost cell turnover), or Azelaic Acid. Often, a dermatologist-prescribed 'triple combination cream' works best. Over-the-counter options containing Vitamin C, Kojic Acid, or Niacinamide can also help. Most importantly, she must apply a broad-spectrum sunscreen (SPF 30 or higher) daily, as UV exposure worsens pigmentation and makes treatments ineffective. Avoid using strong steroid creams without medical supervision.

To treat hyperpigmentation and dark spots, a combination of sun protection and targeted topical ingredients is most effective. First, apply a broad-spectrum sunscreen (SPF 30+) daily, as UV light prevents healing. For active treatments, look for creams containing: 1. Hydroquinone (2-4 percent): The gold standard for fading spots (use short-term under medical guidance). 2. Retinoids (Tretinoin or Retinol): To speed up cell turnover. 3. Brighteners: Azelaic acid, Kojic acid, Vitamin C, or Niacinamide, which inhibit pigment production. 4. AHAs (Glycolic acid): To exfoliate dark surface cells. Always introduce new products gradually, and consult a dermatologist for a tailored prescription regimen.

There is no conclusive evidence that Melalite Forte Cream (Hydroquinone) causes skin cancer in humans. However, prolonged use may cause sun sensitivity, skin thinning, irritation, dryness, and ochronosis (a permanent bluish-black skin discolouration). Use only as prescribed and avoid long-term unsupervised application.

Spots around the hands, legs, and eyes are often due to pigmentation, sun exposure, or conditions like Melasma, so the most important step is daily sunscreen use along with gentle skin care and avoiding harsh products. You can use doctor-advised creams containing agents like kojic acid or azelaic acid to gradually lighten spots.

Facial pigmentation or dark patches can occur due to sun exposure, acne marks, hormonal changes, melasma, skin irritation, allergy, or repeated use of unsuitable creams. Since you have already tried many ointments without much improvement, it is important to first identify the exact cause of the pigmentation before continuing treatment. One of the most important steps is regular sun protection, because sunlight can make pigmentation darker and harder to treat. Use a broad-spectrum sunscreen with SPF 30 or higher every day, even while indoors or during cloudy weather, and reapply it if you stay outside for long periods. Wash your face with a gentle face wash twice daily and avoid harsh scrubbing, strong bleaching creams, or steroid-containing creams without medical advice, as these may worsen pigmentation over time. Creams containing ingredients such as vitamin C, niacinamide, azelaic acid, kojic acid, or mild retinoids may help gradually reduce pigmentation, but improvement usually takes several weeks to months and should be done carefully to avoid irritation. Eating a healthy diet, drinking enough water, sleeping well, and managing stress may also support skin health. If the pigmentation is spreading, associated with itching, or not improving despite regular care, you should consult a dermatologist. The doctor can examine your skin closely and decide whether you have melasma, post-acne pigmentation, allergy-related pigmentation, or another skin condition, and may suggest prescription creams, chemical peels, or other treatments if needed. Avoid expecting instant results, because pigmentation treatment usually requires patience and consistent skin care.