While experiencing bleeding after taking Meprate (medroxyprogesterone acetate) is generally a reassuring sign, a single dose is highly unlikely to trigger a true menstrual period. This bleeding could actually be spotting or due to other hormonal fluctuations, so it does not 100% guarantee she is not pregnant. To give you both peace of mind and get an accurate answer, the best step is for her to take a home pregnancy test, ideally 14 days after you last had intercourse.
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Does getting a period after taking one dose of Meprate 10 mg guarantee that my girlfriend is not pregnant?