Since you have had three negative pregnancy tests, it is highly unlikely that you are pregnant. The brown, creamy spotting you are experiencing after taking Meprate (medroxyprogesterone acetate) is actually a common reaction. This is often 'old blood' shedding as your body responds to the hormone shift, which can occur before your full flow starts or even serve as your light withdrawal bleed if your uterine lining was thin. This is a very normal response to the medication. Please reach out to your healthcare provider if the spotting continues for more than a week or if you experience severe pain.

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Typically, withdrawal bleeding after finishing medroxyprogesterone (Meprate) can take anywhere from 3 to 14 days to start, so at six days, you are still within a normal window. Since your pregnancy tests following your July 22nd intercourse are negative, pregnancy is highly unlikely. Other common reasons for the delay include low estrogen levels (where the uterine lining is too thin to shed), stress, or a hormonal imbalance. Please try to relax and give your body a few more days. If bleeding does not begin within two weeks of finishing the medication, please follow up with your doctor.

To delay your period by one week with your 40-day cycle, medroxyprogesterone acetate (Meprate) is typically started 3 days before your expected period?around day 37 of your cycle. You would take it daily for the duration of the delay (about 7 days). Your period should then arrive 2 to 3 days after you stop taking the medication. It is very important to consult your gynecologist before starting to ensure the correct dosage and safety for your body.

Mild spotting is a very common reaction as your hormone levels adjust and your uterine lining stabilizes, especially when dealing with a small fibroid. To safely and completely stop this spotting, I gently recommend reaching out to your gynecologist. They can evaluate your progress and decide if a dosage adjustment or an alternative management plan is best for you, and your doctor will help you find the right balance.

Stopping Meprate (medroxyprogesterone) after two days because your period started is quite common and generally will not affect the accuracy of your Day-3 PCOS hormone tests. Since you only took it for a very short time, it is unlikely to significantly alter your baseline hormone levels. Your body's natural cycle took over, which is a very reassuring sign. Please share this exact timeline with your doctor when they review your results so they have the full context.