Yes, it is still possible to be pregnant if you have been sexually active since your last cycle. The bleeding you experienced after taking Meprate (medroxyprogesterone acetate) was a withdrawal bleed, which does not guarantee that your natural cycles will immediately become regular. Your late period could be due to a new pregnancy or your body returning to its previous irregular pattern. For your peace of mind, I gently recommend taking a home pregnancy test. If it is negative, please consult your doctor to safely discuss your cycle irregularity.

Usually, a withdrawal bleed occurs within 10 days after finishing medroxyprogesterone (Meprate). Since it has been over 80 days, the first step is to take a home pregnancy test if you are sexually active. If that is negative, this delay is likely due to hormonal fluctuations common in PCOD, where estrogen levels might be too low to build the uterine lining. Please consult your gynecologist. They can evaluate your hormones, perform an ultrasound, and safely guide you on the next steps to regulate your cycle. You are not alone, and this can be managed.

It is very common to wait 3 to 10 days after finishing your Meprate (medroxyprogesterone acetate) course before your period starts, so please don't worry. Since you want to get pregnant, your missed periods and thyroid level of 3.9 are important clues. While 3.9 is often in the normal range, doctors generally prefer thyroid levels below 2.5 when planning a pregnancy to support healthy ovulation. I recommend taking a pregnancy test if your period doesn't start within 10 days of finishing the medication, and then consulting your doctor. They can easily help optimize your thyroid and cycles to beautifully support your pregnancy journey.

Since pregnancy is ruled out, the most common reason you haven't experienced withdrawal bleeding after taking medroxyprogesterone acetate (Meprate) is low estrogen levels. In PCOS, the uterine lining needs enough estrogen to build up before progesterone can cause it to shed. Other reasons could include a temporary hormonal fluctuation or stress. As a next step, I highly recommend contacting your healthcare provider. They may suggest checking your hormone levels or trying a combined estrogen-progesterone course to help trigger your cycle.

Failing to bleed after taking medroxyprogesterone acetate (Meprate), especially after prior methylergonovine (Methergine) exposure, suggests we need to look closer at your system. The next recommended step is to consult a gynecologist. They will likely check your hormone levels (such as FSH, LH, prolactin, and thyroid hormones) and perform a pelvic ultrasound. They may also recommend an estrogen-progesterone challenge test to evaluate your uterine lining.

After completing your course of Meprate (medroxyprogesterone acetate), you can generally expect withdrawal bleeding to start within 3 to 7 days, though it can sometimes take up to two weeks. Yes, there is a strong link between irregular periods and weight gain. Hormonal imbalances, such as Polycystic Ovary Syndrome (PCOS) or thyroid changes, can cause both irregular cycles and weight fluctuations. These are very common and manageable concerns. I highly recommend consulting your doctor, who can guide you gently toward the right steps.