Is it safe and clinically appropriate to combine escitalopram (20 mg) and fluvoxamine (titrating up to 100 mg) without tapering the escitalopram for a patient with refractory health anxiety?
Generally, combining escitalopram and fluvoxamine at these doses without tapering is not recommended. Both medications increase serotonin, and taking them together can lead to excessively high serotonin levels. Additionally, fluvoxamine can slow down how your body processes escitalopram, further increasing its levels and potential side effects. To keep you safe and comfortable, it is usually best to gradually taper off one medication before starting another. Please consult your doctor to discuss a safe, step-by-step transition plan.
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Is it safe and clinically appropriate to combine escitalopram (20 mg) and fluvoxamine (titrating up to 100 mg) without tapering the escitalopram for a patient with refractory health anxiety?