What could cause a patient to experience severe emotional blunting, anhedonia, appetite loss, and a new headache radiating from the upper throat to the center of the head after discontinuing escitalopram (Nexito) and methylprednisolone (Metpred) taken for two months, despite a normal brain MRI?
It is very reassuring that your brain MRI is normal, ruling out structural concerns. What you are experiencing is likely a combined withdrawal response. Discontinuing escitalopram (Nexito) can cause discontinuation syndrome, leading to emotional blunting, anhedonia, and headaches. Similarly, stopping methylprednisolone (Metpred) after two months can trigger steroid withdrawal, causing appetite loss and tension-like headaches radiating from the throat. Your body is currently adjusting to the absence of these medications. Please consult your doctor to safely manage these symptoms, as they may suggest a gradual tapering schedule to help you feel like yourself again.