A sudden, week-long headache can stem from several common causes, including tension, sinus inflammation, or even rebound headaches from daily use of pain relievers like nimesulide. Because this is a new symptom for you, it is very important to consult a healthcare professional for a proper evaluation. They will likely perform a physical and neurological exam to safely determine the cause. Please seek immediate medical attention if you experience any 'red flags' like vision changes, fever, or neck stiffness.

Yes, it is entirely safe for you to get any approved COVID-19 vaccine, as none of them contain paracetamol. Since you have a paracetamol allergy, you can manage a post-vaccine fever with ibuprofen, which is a safe generic alternative. You can also take NISE (nimesulide) for fever and pain, provided you do not have any known allergies to nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin or ibuprofen. Always stay well-hydrated, rest, and consult your doctor to confirm the safest option and correct dosage for your specific health history.

Your symptoms of recurring fever, chills, sweating, and joint pain suggest an underlying infection such as malaria, dengue, chikungunya, or a bacterial illness. Nise (nimesulide) only temporarily masks the pain and fever but will not cure the underlying cause. Self-medicating with stronger drugs is unsafe and can be harmful. I strongly advise you to consult a healthcare professional immediately. You need diagnostic blood tests (like a complete blood count, malaria, or dengue test) to identify the specific cause. Once diagnosed, a doctor will prescribe the appropriate targeted treatment, such as antibiotics or antimalarials. Please stay well-hydrated and rest until you see a doctor.

Taking Nise (nimesulide) for just two days is very unlikely to cause your period to be late. Nimesulide is an anti-inflammatory painkiller, and while these medications can sometimes mildly affect ovulation, a short course rarely impacts your menstrual cycle. Often, the physical stress of the underlying pain or illness that prompted you to take the medication is the actual reason for the delay. Please try not to worry. If your period is delayed by more than a week, a quick home pregnancy test or a chat with your doctor can provide peace of mind.

Since your congestion hasn't improved with sprays, drops, or steam, the blockage is likely due to an issue inside the nasal passages, such as swelling of the lining, nasal polyps, or a deviated septum. I understand how frustrating this persistent blockage must be. Please consider seeing an ear, nose, and throat (ENT) specialist. They can gently examine both your nose and throat to find the exact cause and help you find relief.

It is very common for COVID-19 to cause severe throat inflammation, which can make swallowing painful and cause referred pain in your brother's left ear. The feeling of something being stuck can happen due to intense swelling or if medications like cefuroxime (Ceftum) or nimesulide (Nise) slightly irritated his food pipe. Please reassure him that this is a recognized pattern. Taking his medications with plenty of water and sipping warm liquids can help. However, since swallowing liquids is extremely difficult, please consult his doctor promptly to ensure he stays hydrated and to see if his treatment needs adjusting.