Your symptoms of thick, yellowish discharge suggest significant inflammation, possibly due to chronic sinusitis or allergies. Deflazacort, which is a corticosteroid, works by powerfully reducing this severe swelling in your nasal passages, which is why it brings you relief. However, using oral steroids long-term is not recommended. I highly encourage you to consult an ear, nose, and throat specialist. They can pinpoint the exact cause and recommend safer, localized treatments like steroid nasal sprays or saline rinses to help you breathe easily and safely.

Yes, it is entirely safe for you to get any approved COVID-19 vaccine, as none of them contain paracetamol. Since you have a paracetamol allergy, you can manage a post-vaccine fever with ibuprofen, which is a safe generic alternative. You can also take NISE (nimesulide) for fever and pain, provided you do not have any known allergies to nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin or ibuprofen. Always stay well-hydrated, rest, and consult your doctor to confirm the safest option and correct dosage for your specific health history.

Taking Nise (which contains nimesulide) daily over a long period can carry risks for your stomach and liver, so it should be monitored closely. Since your joint and back pain are worsening, it is very important to consult a healthcare professional. They can properly evaluate your heel, knee, and old wrist fracture to find the root cause of the inflammation. A doctor can guide you on safer, long-term treatment plans, which might include targeted physical therapy and gentler medications, and let a doctor help you safely find relief.

Please do not take any more medicines. Wikoryl already contains paracetamol, an antihistamine, and a decongestant, while Nise contains nimesulide, a strong painkiller. Combining these two medications already puts you at risk of therapeutic duplication, which can strain your liver and kidneys. Adding more self-prescribed drugs can be dangerous. Instead, rest, stay hydrated with warm fluids, and try steam inhalation for nasal congestion. If your fever and cold do not improve within 48 hours, or if you develop new symptoms like breathlessness, please consult a doctor immediately for a proper evaluation and safe prescription.

Taking Nise (nimesulide) for just two days is very unlikely to cause your period to be late. Nimesulide is an anti-inflammatory painkiller, and while these medications can sometimes mildly affect ovulation, a short course rarely impacts your menstrual cycle. Often, the physical stress of the underlying pain or illness that prompted you to take the medication is the actual reason for the delay. Please try not to worry. If your period is delayed by more than a week, a quick home pregnancy test or a chat with your doctor can provide peace of mind.

It is quite common to experience lingering rib pain after recovering from COVID-19, often due to localized inflammation of the cartilage (costochondritis) or muscle strain from coughing. Sleeping on your left side puts pressure on this tender area, worsening the discomfort. While Nise (nimesulide) is effective for reducing this pain and inflammation, it is a strong medication and should not be used long-term without medical supervision, as prolonged use can affect your stomach and liver. Please consult your doctor for a safe, personalized treatment plan. In the meantime, try sleeping on your back or right side to ease the pressure.