Yes, it is possible for these medications to cause diarrhea. Specifically, Normaxin RT, which contains an acid-reducer (rabeprazole) and a medicine that speeds up gut movement (itopride), is a common culprit for loose stools. While Sucrafil O gel (sucralfate and oxetacaine) and Digeraft (sodium alginate) are more commonly known to cause constipation, any change in your digestive routine can occasionally trigger mild diarrhea. It is important to stay well-hydrated. If the diarrhea becomes severe or does not improve, please contact your doctor to safely discuss alternative options.