For a severe cold with sinus blockage, you can use a generic oral decongestant like pseudoephedrine or a nasal spray like oxymetazoline (limit nasal spray use to 3 consecutive days to prevent worsening congestion). For sinus pain or headache, over-the-counter pain relievers such as acetaminophen or ibuprofen can help. Using a saline nasal spray or rinse is also a safe, drug-free way to clear mucus. Be sure to stay hydrated and rest. If your symptoms worsen, you develop a high fever, or they last longer than 10 days, please consult a healthcare professional for a proper evaluation.
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I have a severe cold with sinus blockage, what medicine should I take?