Your elevated IgE level of 457 suggests an underlying allergic response. Hydroxyzine, the medication you are taking, provides only temporary relief. For safer, long-term management, daily use of second-generation, non-sedating antihistamines like levocetirizine, fexofenadine, or loratadine is often recommended under medical supervision. Keeping your skin well-hydrated with fragrance-free moisturizers also significantly reduces itching. To find a more permanent solution, it is highly recommended to consult a dermatologist or allergist. They can help identify specific allergy triggers through testing and tailor a long-term treatment plan. Please do not worry, as chronic itching is highly manageable with the right daily strategy.