I underwent an angioplasty in 2014 for an 85% blockage, but I still experience persistent chest pain despite having normal annual 2D Echo results. Since my current medications have not provided relief for the past two years, what alternative cardiac medications or pharmaceutical treatments should I discuss with my doctor to help manage this ongoing pain?

It is reassuring that your 2D Echo shows normal heart function, but persistent pain requires a review. This discomfort can sometimes be due to microvascular angina (small blood vessel issues) or spasms, which an Echo cannot detect. You should discuss alternative anti-anginal therapies with your doctor. Generic medications such as ranolazine (which improves myocardial oxygen use), ivabradine (to lower heart rate), nicorandil, or long-acting nitrates might be beneficial. Your cardiologist may also recommend a stress test or a coronary angiogram to evaluate the blood flow directly. Please do not adjust your current medications without medical supervision.